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Diastolic blood pressure-estimated left ventricular dp/dt
Hüseyin Yilmaz1, Kenan Minareci, Mehmet Kabukçu
1Akdeniz University, Department of Cardiology, Antalya, Turkey. drhy@um.turkcell.com.tr
Echocardiography (Mount Kisco, N.Y.)
|April 3, 2002
Summary
Noninvasive estimation of left ventricular dp/dt using diastolic blood pressure (DBP) and isovolumetric contraction time (IVCT) highly correlates with Doppler echocardiography methods. This offers a clinically feasible approach for assessing myocardial contractility without invasive procedures.
Area of Science:
- Cardiology
- Echocardiography
- Hemodynamics
Background:
- Left ventricular dp/dt is a key indicator of myocardial contractility.
- Current methods for measuring left ventricular dp/dt are often invasive or require severe mitral regurgitation.
- Noninvasive assessment of myocardial function is clinically valuable.
Purpose of the Study:
- To evaluate the correlation between two noninvasive methods for measuring left ventricular dp/dt.
- To assess the clinical feasibility of diastolic blood pressure (DBP)-estimated left ventricular dp/dt.
- To compare DBP-estimated dp/dt with continuous-wave Doppler-derived dp/dt.
Main Methods:
- Thirty-six patients with mild mitral regurgitation were studied.
- DBP-estimated dp/dt was calculated using DBP, assumed left ventricular end-diastolic pressure (LVEDP), and isovolumetric contraction time (IVCT).
- Doppler-determined dp/dt was derived from the mitral regurgitation jet velocity using continuous-wave Doppler.
Main Results:
- Left ventricular dp/dt by Doppler was 1122 +/- 303 mmHg/sec.
- Blood pressure-estimated dp/dt was 1063 +/- 294 mmHg/sec.
- A high correlation (r = 0.97, P < 0.001) was found between the two measurement techniques.
Conclusions:
- Diastolic blood pressure (DBP) and isovolumetric contraction time (IVCT) can be used to estimate left ventricular dp/dt noninvasively.
- This DBP-estimated method is clinically feasible for assessing myocardial contractility.
- The technique is applicable even without significant mitral regurgitation.