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Updated: Aug 9, 2026

Primary Culture of Human Vestibular Schwannomas
Published on: July 20, 2014
[Multifocal localization of tumors of Schwann cell origin]
Z Milutinović1, M Vidojević, Z Trifković
1Ward of Oto-rhino-laryngology, Maxillar Surgery and Cervical Pathology, Zemun Clinical and Hospital Centre, Belgrade.
Abstract:
Neurofibromatosis (disease of Von Recklinghausen) was considered to be a unique disease. Today, however, it is known that it consist of two clinically and genetically different diseases. Neurofibromatosis type 1 is a more frequent disease formerly known as peripheral, while neurofibromatosis type 2 (bilateral acoustic neurinoma) is significantly less frequent. In this case report we present a 30-year old female patient who had several tumours with the following localizations: 1. the pontocerebellar angulus; 2. the left foramen jugular; 3. the anterior part of the spinal canal; 4. the soft tissue of the neck; 5. falx cerebri. The tumor in the neck was removed completely by ENT surgeon while the others were partly removed by neurosurgeon. In this case report we described diagnostic and therapeutic problems in the treatment of this patient with the long-lasting hoarseness and difficult swallowing.

