Pasteurella multocida septicaemia in 2 Swedish patients

Andreas Berge1, Anna Fagergren, Susanne Hammers Stiernstedt

  • 1Divisions of Infectious Diseases, Karolinska Institutet, Karolinska Hospital, Stockholm.

Insights

Human infections with Pasteurella multocida typically cause cellulitis, but rarely lead to septicaemia. This report details two rare cases of Pasteurella multocida septicaemia in Swedish patients.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Clinical Medicine

Background:

  • Pasteurella multocida is a Gram-negative bacterium commonly found in animal respiratory tracts.
  • Human infections with P. multocida usually manifest as localized cellulitis, often following animal bites or scratches.
  • Septicemia (bloodstream infection) caused by P. multocida is an uncommon but serious clinical presentation.

Observation:

  • Two distinct cases of P. multocida septicaemia occurred in patients within the same hospital ward over a seven-month period.
  • Both patients presented with severe systemic infection, deviating from the usual clinical presentation.

Findings:

  • The study highlights the rare occurrence of P. multocida septicaemia.
  • The simultaneous admission of two such cases in the same ward suggests potential localized transmission or a shared environmental/epidemiological factor.
  • Detailed clinical and microbiological data were collected for both patients.

Implications:

  • This case series underscores the importance of considering P. multocida as a potential cause of septicaemia, even if rare.
  • Further investigation into potential transmission routes and risk factors for severe P. multocida infections is warranted.
  • Clinicians should maintain a high index of suspicion for P. multocida septicaemia in relevant patient populations.