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Pasteurella multocida septicaemia in 2 Swedish patients
Andreas Berge1, Anna Fagergren, Susanne Hammers Stiernstedt
1Divisions of Infectious Diseases, Karolinska Institutet, Karolinska Hospital, Stockholm.
Abstract:
The clinical manifestation of human infections with Pasteurella multocida is most often cellulitis and this pathogen rarely causes septicaemia. We describe 2 Swedish patients with P. multocida septicaemia who were admitted to the same ward within the space of 7 months.
Insights
Human infections with Pasteurella multocida typically cause cellulitis, but rarely lead to septicaemia. This report details two rare cases of Pasteurella multocida septicaemia in Swedish patients.
Area of Science:
- Infectious Diseases
- Microbiology
- Clinical Medicine
Background:
- Pasteurella multocida is a Gram-negative bacterium commonly found in animal respiratory tracts.
- Human infections with P. multocida usually manifest as localized cellulitis, often following animal bites or scratches.
- Septicemia (bloodstream infection) caused by P. multocida is an uncommon but serious clinical presentation.
Observation:
- Two distinct cases of P. multocida septicaemia occurred in patients within the same hospital ward over a seven-month period.
- Both patients presented with severe systemic infection, deviating from the usual clinical presentation.
Findings:
- The study highlights the rare occurrence of P. multocida septicaemia.
- The simultaneous admission of two such cases in the same ward suggests potential localized transmission or a shared environmental/epidemiological factor.
- Detailed clinical and microbiological data were collected for both patients.
Implications:
- This case series underscores the importance of considering P. multocida as a potential cause of septicaemia, even if rare.
- Further investigation into potential transmission routes and risk factors for severe P. multocida infections is warranted.
- Clinicians should maintain a high index of suspicion for P. multocida septicaemia in relevant patient populations.
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