Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fetal pharmacotherapy.

Gideon Koren1, Gil Klinger, Arne Ohlsson

  • 1Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada. gkoren@sickkids.on.ca

Drugs
|April 4, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early versus late erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants.

The Cochrane database of systematic reviews·2020
Same author

Early erythropoiesis-stimulating agents in preterm or low birth weight infants.

The Cochrane database of systematic reviews·2020
Same author

Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants.

The Cochrane database of systematic reviews·2020
Same author

Surfactant for pulmonary haemorrhage in neonates.

The Cochrane database of systematic reviews·2020
Same author

Intravenous immunoglobulin for suspected or proven infection in neonates.

The Cochrane database of systematic reviews·2020
Same author

Intravenous immunoglobulin for preventing infection in preterm and/or low birth weight infants.

The Cochrane database of systematic reviews·2020
Same journal

The Long Road to Long-Acting: What Oral PrEP and CAB-LA Teach Us About Scaling Lenacapavir.

Drugs·2026
Same journal

Botulinum Toxin Type A for Trigeminal and Postherpetic Neuralgia: An Umbrella Review of Systematic Reviews.

Drugs·2026
Same journal

Biologics and Small Molecule Inhibitors: Novel Therapeutic Strategies for Cutaneous Adverse Drug Reactions.

Drugs·2026
Same journal

Use of Sedative-Hypnotic Drugs and the Risk of Developing Alzheimer's Disease: A Systematic Review, Meta-Analysis and Meta-Regression.

Drugs·2026
Same journal

Relacorilant: First Approval.

Drugs·2026
Same journal

Developmental Progress and Future Potential for Inhaled Biologics in the Treatment of Respiratory Diseases.

Drugs·2026
See all related articles

Fetal pharmacotherapy offers promising treatments for unborn babies, but requires careful consideration of drug transfer, ethical implications, and robust scientific methodology for safe and effective outcomes.

Area of Science:

  • Pharmacology
  • Maternal-Fetal Medicine
  • Developmental Biology

Background:

  • Pharmacological treatment of the unborn baby is rapidly advancing.
  • This field presents unique methodological and ethical challenges.
  • Understanding maternal-to-fetal drug transfer is crucial.

Purpose of the Study:

  • To systematically review fetal pharmacotherapy modalities.
  • To highlight key principles, difficulties, and controversies.
  • To emphasize the need for optimal methodology in fetal drug therapy.

Main Methods:

  • Systematic review of existing literature on fetal pharmacotherapy.
  • Analysis of pharmacokinetic factors influencing drug transfer.
  • Evaluation of methodological approaches and ethical considerations.

Related Experiment Videos

Main Results:

  • Corticosteroids for lung maturation exemplify successful fetal therapy.
  • Phenobarbital's antenatal use highlights suboptimal methodology.
  • Folic acid demonstrates prevention of major fetal malformations.
  • Infections like HIV necessitate controlled studies for prevention.

Conclusions:

  • Adherence to rigorous methodology is essential for effective fetal pharmacotherapy.
  • Informed consent and ethical considerations are paramount.
  • Future fetal therapies require robust study designs to meet fetal needs.