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[Anorectic syndrome].

G Zürcher1

  • 1Sektion Ernährungsmedizin und Diätetik, Abt. Innere Medizin 1, Universitätsklinikum Freiburg, Germany. zuercher@mm11.ukl.uni-freiburg.de

Zeitschrift Fur Gastroenterologie
|April 4, 2002
PubMed
Summary

Cancer patients often experience anorexia, a complex syndrome of appetite loss and taste changes. Its multifactorial causes and various treatment options are crucial for managing malignant diseases.

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Area of Science:

  • Oncology
  • Gastroenterology
  • Nutrition Science

Context:

  • Anorectic syndrome is a common symptom in patients with malignant diseases.
  • It involves appetite loss, food aversion, and sensory disturbances.
  • Anorexia prevalence increases with tumor stage, affecting ~40% at diagnosis.

Purpose:

  • To define anorectic syndrome in cancer patients.
  • To explore the multifactorial etiology of cancer-induced anorexia.
  • To outline current treatment strategies for anorexia in malignancy.

Summary:

  • Anorexia in cancer is characterized by decreased food intake (<80% usual).
  • Causes are diverse, including tumor-specific factors, metabolic changes, psychological elements, and treatment side effects.
  • Nutritional interventions and pharmacotherapy (prokinetics, corticosteroids, gestagens, cannabinoids) are key treatment approaches.

Impact:

  • Understanding anorexia is vital for improving cancer patient quality of life.
  • Effective management can mitigate malnutrition and treatment complications.
  • Further research into anorexia's complex mechanisms can lead to novel therapeutic targets.

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