[Oro-antral perforations. Desirability of antibiotic support in surgical closure within 24 hours]
1Afdeling Mondziekten en Kaakchirurgie/Orale Pathologie, Academisch Centrum Tandheelkunde Amsterdam/Academisch Ziekenhuis, Vrije Universiteit Amsterdam, postbus 7057, 1007 MB Amsterdam.
Objective:
The routine use of antibiotics in oro-antral perforations is advocated by a number of authors, in order to prevent post-operative complications such as sinusitis. Our aim was to establish wether the preventive use of antibiotics seams to be indicated in the closure of this perforations.
Design:
A retrospective investigation.
Setting:
The department of Oral and Maxillofacial Surgery and Oral Pathology of the Academic Center for Dentistry Amsterdam (ACTA) and the Free University Hospital Amsterdam.
Methods:
In a retrospective study 46 patients have been investigated, 32 males and 14 females, who underwent a surgical closure of an oro-antral perforation in 1995, within 24 hours after its occurrence, in a department of oral and maxillofacial surgery. Twenty-two patients received preoperative antibiotics and 24 patients were treated without the use of antibiotics.
Results:
Three (6.5%) patients had a post-operative sinusitis. In the other 43 patients there were no postoperative complications.
Conclusion:
The preventive use of antibiotics in oro-antral perforations in order to prevent post-operative complications such as sinusitis seams not to be indicated in the closure of this perforations. However, before a final conclusion on this matter can be drawn, a prospective randomized study should be undertaken.
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