Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Avian metabolism of halogenated biphenyls.

D H Jones, J Kohli, S Safe

    Xenobiotica; the Fate of Foreign Compounds in Biological Systems
    |December 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Black Hole Spectroscopy and Tests of General Relativity with GW250114.

    Physical review letters·2026
    Same author

    GW250114: Testing Hawking's Area Law and the Kerr Nature of Black Holes.

    Physical review letters·2025
    Same author

    Improving cosmological reach of a gravitational wave observatory using Deep Loop Shaping.

    Science (New York, N.Y.)·2025
    Same author

    Algorithmic assessment of cellular senescence in experimental and clinical specimens.

    Nature protocols·2021
    Same author

    Auditory time perception in Huntington's disease.

    Neuropsychologia·2018
    Same author

    SEPN1-related myopathies: clinical course in a large cohort of patients.

    Neurology·2011

    Poultry metabolize halogenated biphenyls into hydroxylated compounds. No detectable metabolites were found in eggs within seven days of administration.

    Area of Science:

    • Environmental Chemistry
    • Toxicology
    • Biochemistry

    Background:

    • Halogenated biphenyls (HBs) are persistent environmental pollutants.
    • Understanding their metabolic fate is crucial for risk assessment.
    • Poultry offer a relevant model for studying HB metabolism.

    Purpose of the Study:

    • To investigate the metabolic pathways of specific halogenated biphenyls in poultry.
    • To identify and characterize the resulting metabolites.
    • To determine the presence of these metabolites in poultry eggs over time.

    Main Methods:

    • Administration of 4-chlorobiphenyl, 4-bromobiphenyl, and 4,4'-dichlorobiphenyl to poultry.
    • Analysis of tissue samples for metabolite identification.
    • Monitoring of poultry eggs for metabolite presence for seven days post-administration.

    Related Experiment Videos

    Main Results:

    • 4-chlorobiphenyl yielded 4'-chloro-4-biphenylol and 4'-chloro-3,4-biphenyldiol.
    • 4-bromobiphenyl yielded 4'-bromo-4-biphenylol and 4'-bromo-3,4-biphenyldiol.
    • 4,4'-dichlorobiphenyl yielded 4,4-dichloro-3-biphenylol.
    • No metabolites were detected in eggs within the 7-day sampling period.

    Conclusions:

    • Poultry can metabolize certain halogenated biphenyls into hydroxylated derivatives.
    • The specific metabolites formed depend on the structure of the parent compound.
    • Halogenated biphenyls and their metabolites are not readily transferred to eggs in the short term studied.