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Group II phospholipase A2 content of tears in patients with senile cataract and primary open-angle glaucoma
V V Aho1, T J Nevalainen, V Paavilainen
1Department of Ophthalmology, University of Turku, Finland.
Purpose:
To determine the group II phospholipase A2 (PLA2) content of tears in patients with senile cataract or primary open-angle glaucoma (POAG) and to compare it with the PLA2 content of tears in age-matched healthy controls.
Methods:
The PLA2 concentration of tears was measured with time-resolved fluoroimmunoassay in 21 patients with senile cataract, 23 patients with POAG and in 40 healthy controls.
Results:
The PLA2 content of tears was 38.3+/-30.1 microg/ml in patients with senile cataract, 32.1+/-22.3 microg/ml in patients with POAG, and 36.6+/-31.1 microg/ml in healthy controls. There were no significant differences between the patient and the control groups.
Conclusions:
We conclude that neither senile cataract nor POAG has any effect on the PLA2 content of tears.
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