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[Celecoxib induced toxiderma with positive patch-test].

S Verbeiren1, C Morant, H Charlanne

  • 1Service de Dermatologie, Centre Hospitalier Saint-Philibert, Université Catholique de Lille, 115, rue du Grand But, BP 249, 59462 Lille.

Annales De Dermatologie Et De Venereologie
|April 9, 2002
PubMed
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A maculopapular rash developed in a patient taking celecoxib, a non-steroidal anti-inflammatory drug. Positive patch tests confirmed celecoxib as the cause, highlighting potential cutaneous reactions.

Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Celecoxib (Celebrex®) is a new-generation non-steroidal anti-inflammatory drug (NSAID).
  • NSAIDs are commonly prescribed for pain and inflammation.

Observation:

  • A 40-year-old male developed a maculopapular rash after nine days of celecoxib treatment.
  • The rash resolved within a week of discontinuing the medication.

Findings:

  • Patch testing with celecoxib yielded a positive result at 48 hours.
  • The clinical presentation and diagnostic tests strongly implicated celecoxib.

Implications:

  • This case underscores the potential for cutaneous adverse reactions to celecoxib.
  • Healthcare providers should consider NSAID-induced rashes in patients presenting with similar symptoms.

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