Related Experiment Video
Updated: Aug 14, 2026

A Murine Closed-chest Model of Myocardial Ischemia and Reperfusion
Published on: July 17, 2012
[Apoptosis in myocardial ischemia and reperfusion]
Abstract:
Apoptosis initiated in cells of tissues maintaining homeostasis under the influence of growth factors and hormones has been recently described during the early stage of myocardial infarction in the reperfusion zone of the cardiac muscle. Although it has been proved that apoptosis of cardiomyocytes plays one of the key roles in progression of the reperfusion syndrome, molecular and cellular mechanisms of this phenomenon are not yet resolved. Prospects are discussed of a new trend in preventive treatment of ischemic and reperfusion-related affection of the myocardium relying upon blocking of apoptosis of cardiomyocytes.
Related Concept Videos
Apoptosis
The Intrinsic Apoptotic Pathway
Necrosis
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become anucleated and die, but their...
Myocarditis I: Introduction
Cellular Injury IV: Necrosis
Cellular Injury V: Apoptosis and Autophagy

