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Related Experiment Videos

Neocortex and feeding behavior in the rat.

J J Braun

    Journal of Comparative and Physiological Psychology
    |August 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Neocortical ablations in rats significantly impacted feeding and drinking behaviors, leading to reduced body weight regulation and altered consummatory patterns. Lesion size correlated with the severity of these long-term effects.

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    Area of Science:

    • Neuroscience
    • Behavioral Neuroscience
    • Physiology

    Background:

    • The lateral hypothalamus is a critical area for regulating consummatory behaviors and body weight.
    • The role of the neocortex in these regulatory functions is less understood.
    • Previous research has primarily focused on hypothalamic lesions.

    Purpose of the Study:

    • To investigate the effects of neocortical ablations on consummatory behavior and body weight regulation in rats.
    • To compare the effects of different patterns of neocortical damage (complete, unilateral, anterolateral, posterior).

    Main Methods:

    • Surgical ablation of specific neocortical areas in rats.
    • Measurement of consummatory behaviors (feeding, drinking).
    • Assessment of body weight regulation capacity and body-weight set point.

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  • Observation of recovery stages post-lesion.

    • Main Results:

    • Complete (C) and anterolateral (A) neocortical ablations resulted in aphagia and adipsia, followed by a shortened recovery similar to hypothalamic lesions.
    • Group C exhibited long-term finickiness and reduced body weight regulation, with effects correlating to lesion size and a lower body-weight set point.
    • Unilateral ablations (U) had minimal initial effects, but bilateral damage led to long-term deficits; posterior ablations (P) showed less severe and distinct effects.

    Conclusions:

    • The neocortex plays a significant role in the neural control of consummatory behavior and body weight regulation.
    • The pattern and extent of neocortical damage influence the severity and nature of behavioral and regulatory deficits.
    • Neocortical lesions can induce long-lasting alterations in feeding, drinking, and body weight maintenance.