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[Use of lactusan for the correction of microecological intestinal disturbances in children]

V E Rodoman1, V I Maksimov, L G Kuz'menko

  • 1Peoples' Friendship University, Moscow, Russia.

Zhurnal Mikrobiologii, Epidemiologii I Immunobiologii
|April 16, 2002
PubMed

Insights

Lactusan (lactulose) effectively treated dysbacteriosis in children, reducing diarrhea and improving gut bacteria. This prebiotic shows promise for pediatric gut health management.

Area of Science:

  • Pediatric Gastroenterology
  • Microbiology
  • Nutritional Science

Background:

  • Dysbacteriosis, an imbalance in gut microbiota, is common in children.
  • Effective treatments for pediatric dysbacteriosis are needed to improve gut health and reduce symptoms like diarrhea.

Purpose of the Study:

  • To evaluate the efficacy of lactusan (lactulose) as a treatment for dysbacteriosis in pediatric patients.
  • To assess the impact of lactulose on clinical symptoms and gut microbial composition.

Main Methods:

  • A study involving 24 sick children aged 1 month to 15 years with dysbacteriosis.
  • Administration of lactusan (lactulose) to 21 patients.
  • Monitoring of clinical symptoms, particularly diarrhea.
  • Analysis of fecal samples to assess changes in bifidobacteria, lactic acid bacteria, and opportunistic microorganisms.

Main Results:

  • Perceptible improvement in clinical symptoms, primarily cessation of diarrhea, was observed in 21 out of 24 patients.
  • Increased populations of beneficial bifidobacteria and lactic acid bacteria were noted in 14 children.
  • A decrease in the number of opportunistic microorganisms was observed in the same group of 14 children.

Conclusions:

  • Lactusan (lactulose) is an effective remedy for pediatric dysbacteriosis.
  • Lactulose administration positively modulates gut microbiota, increasing beneficial bacteria and reducing harmful ones.
  • Lactulose should be classified as a prebiotic due to its beneficial effects on gut microflora.

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