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Updated: Jun 30, 2026

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study
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[Current researches in keratoprosthesis].

Hongxia Zhao1, Deming Xie, Han Zou

  • 1Biomedical Engineering Institute, Jinan University, Guangzhou 510632.

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi = Journal of Biomedical Engineering = Shengwu Yixue Gongchengxue Zazhi
|April 16, 2002
PubMed
Summary

This study reviews keratoprosthesis evolution, highlighting drawbacks and ideal properties for artificial cornea devices. Current research explores porous polymers to enhance integration in core-skirt keratoprosthesis designs.

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Area of Science:

  • Ophthalmology
  • Biomaterials Science
  • Regenerative Medicine

Context:

  • The limitations of traditional corneal transplantation necessitate advanced solutions.
  • Keratoprosthesis (KP) devices offer an alternative for severe corneal blindness.
  • Tissue engineering presents a promising avenue for artificial cornea development.

Purpose:

  • To trace the historical development of keratoprosthesis devices.
  • To identify the shortcomings of current and historical keratoprosthesis designs.
  • To outline the essential characteristics for an ideal artificial cornea, including tissue-engineered options.

Summary:

  • The paper details the evolution of keratoprosthesis from early designs to modern iterations.
  • Drawbacks of existing devices are discussed, alongside the required properties for optimal performance.

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  • Recent advancements focus on porous polymers for core-skirt keratoprosthesis skirts to improve biological integration.

    • Impact:

    • Provides a comprehensive overview of keratoprosthesis technology for researchers and clinicians.
    • Highlights key areas for future development in artificial cornea materials and design.
    • Informs the design of next-generation keratoprosthesis with enhanced biocompatibility and integration.