Related Experiment Video

Updated: Jul 11, 2026

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications
09:39

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications

Published on: January 27, 2014

Isoforms of NO-sensitive guanylyl cyclase

Michael Russwurm1, Doris Koesling

  • 1Pharmakologie und Toxikologie, Medizinische Fakultät MA N1, Ruhr-Universität Bochum, Germany. koesling@iname.com

Molecular and Cellular Biochemistry
|April 16, 2002
PubMed
Summary

Nitric oxide (NO)-sensitive guanylyl cyclase is crucial for vascular regulation. New research suggests the alpha2beta1 isoform interacts with PSD-95, potentially localizing it near NO synthase for enhanced signaling.

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