[Overweight--problem in pediatric patients. Part I. Obesity as a risk factor for metabolic disturbances]

Obesity in adults is associated with multiple disorders of glucose, insulin and lipid homeostasis. Children with early onset of obesity appear to be an interesting group for study of early alterations in human obesity. However only few such studies have been performed. In this group, many data show that obesity in childhood and adolescents is associated with the development of risk factors for cardiovascular and metabolic diseases. The objective of this study was to determine contribution of obesity to the development of impaired glucose tolerance, dyslipidaemia and hormonal imbalance. Body mass index (BMI) greater than 25 kg/m2 has recommended as the cutoff value respectively for overweight. In obese patients insulin secretion, glucose and lipid metabolism was impaired.