Related Experiment Video
Updated: Aug 14, 2026

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations
Published on: January 10, 2015
Environmental toxicology: polychlorinated biphenyls impair TNF-alpha release in vitro
1Faculty of Veterinary Medicine, Ludwig Maximilians University of Munich, München, Germany. ahne@lrz.uni-muenchen.de
Abstract:
Tumour necrosis factor (TNF-alpha) was induced by bacterial lipopolysaccharides (LPS)/phytohemagglutin (PHA) stimulated human whole blood in vitro. Levels of TNF-alpha were evaluated by enzyme-linked immunosorbent assay. Blood samples treated with polychlorinated biphenyls (PCB 77, PCB 126) exhibited impairment of TNF-alpha release: 50 pg/microl PCB reduced by up to 66% and 500 pg/microl PCB reduced by up to 93% the TNF-alpha release compared with the controls.
More Related Videos
16:07Determination of the Relative Potency of an Anti-TNF Monoclonal Antibody (mAb) by Neutralizing TNF Using an In Vitro Bioanalytical Method
Published on: September 16, 2017
11:44A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta
Published on: September 27, 2017