[The value of different spiral CT phases in the detection of liver metastases]

To assess the value of the non-contrast phase (NCP), hepatic-arterial phase (HAP) and portal-venous phases (PVP) for the detection of liver metastases by spiral CT.

In order to detect liver metastases, 119 patients (58 women, 61 men; mean age: 62 years) underwent triphasic spiral CT (8 mm collimation, 12 mm table increment/rotation, 7 mm reconstruction increment). NCP, HAP (20 s delay) and PVP (70 s delay) scans were acquired (contrast medium injection rate: 4 ml/s). CT analysis comprised independent evaluation of the three scan series for detection and conspicuity of liver metastases (conspicuity score: 0 = not visible, 1 = barely visible, 2 = clearly visible, 3 = distinctly visible).

In 83 of the 119 patients, 478 liver metastases were detected (110 hypervascular and 368 hypovascular lesions). 285 (60 %) metastases were detected on NCP scans. Significantly more lesions were seen on HAP (n = 375, 78 %) and on PVP (n = 428, 90 %). No lesion was detected on NCP studies alone. For all detected metastases, mean conspicuity was 1.2 +/- 0.4 on NCP, 1.8 +/- 0.8 on HAP and 2.2 +/- 0.8 PVP. Hypervascular lesions were best seen on HAP with a conspicuity score of 2.0 +/- 0.8 versus 1.3 +/- 0.5 on NCP and 1.5 +/- 0.8 on PVP. Hypovascular lesions reached the highest conspicuity on PVP with 2.4 +/- 0.8 versus 1.2 +/- 0.4 on NCP and 1.7 +/- 0.7 on HAP.

For detection of liver metastases with spiral CT, contrast series seem to be sufficient. For tumors likely to seed hypervascular metastases, HAP scans should be applied in addition to the PVP.