[Clinic-pathologic pattern and survival range in resectable gastric carcinoma]

Area of Science:

• Oncology
• Gastroenterology
• Surgical Pathology

Background:

• Gastric carcinoma presents significant challenges in diagnosis and treatment.
• Understanding clinical and pathological features is vital for patient management.
• Survival rates and surgical outcomes vary between resectable and unresectable cases.

Purpose of the Study:

• To evaluate clinical and pathological features of gastric carcinoma.
• To determine actuarial survival rates in resectable and unresectable gastric cancer.
• To analyze surgical morbidity and mortality in gastric cancer patients.

Main Methods:

• Retrospective study of 308 patients with gastric carcinoma (180 resectable, 128 unresectable).
• Data collected from Belen Hospital, Trujillo, Peru (1966-1998).
• Analysis of clinical presentation, pathological staging, survival rates, and surgical complications.

Main Results:

• Unresectable gastric cancer showed higher rates of palpable mass, advanced T-stage (T4), distant metastasis (Stage IV), and specific metastases (hepatic, peritoneal).
• Total surgical mortality was 19.5% (12.1% in resectable, 28.9% in unresectable).
• Common complications included pneumonia and surgical wound infection; 5-year survival for resectable was 18.5%, while 36-month survival for unresectable was 0%.

Conclusions:

• Unresectable gastric carcinoma is associated with poorer prognostic indicators and higher mortality.
• Surgical interventions in unresectable cases, including palliative procedures, carried significant risks.
• Early diagnosis of gastric cancer, particularly in high-risk individuals, is essential for improving treatment efficacy and survival.