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[Antimutagenic properties of bacteria: a review]
1Department of Microbiology, Moscow State University, Moscow, 119899 Russia. mina@nvorobjeva.home.bio.msu.ru
Prikladnaia Biokhimiia I Mikrobiologiia
|April 19, 2002
Abstract:
Lactic acid and propionic acid bacteria, bifidobacteria, and fecal enterococci associated with the activity of humans and animals caused antimutagenic effects (AME) on many test systems designed for detecting point mutations and chromosomal aberrations. Bacterial cells and some of their metabolites attenuate the mutagenic action of several genotoxic agents, and this effect is mediated by the mechanism of dysmutagenesis and/or bioantimutagenesis. Possible mechanisms of various AMEs and possible practical applications of antimutagenic properties of bacteria are discussed.