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Circulatory adaptive reactions under hypergravity in normal and cold environments.

P Groza1, E Daneliuc, E Nicolescu

  • 1Institute of Physiology, Bucharest, Rumania.

Life Sciences and Space Research
|January 1, 1977
PubMed
Summary

Exposure to +Gz acceleration in rats triggers a sympatho-adrenergic response, increasing stress hormones. This also elevates antidiuretic hormone levels, which are lessened in colder conditions.

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Area of Science:

  • Physiology
  • Aerospace Medicine
  • Endocrinology

Background:

  • +Gz acceleration impacts physiological responses.
  • The sympatho-adrenergic system and antidiuretic hormone play roles in stress.
  • Environmental factors can modulate these responses.

Purpose of the Study:

  • To investigate the physiological effects of +Gz acceleration on rats.
  • To examine the relationship between sympatho-adrenergic activity and antidiuretic response.
  • To assess the influence of cold environment on these responses.

Main Methods:

  • Rats were exposed to varying levels of +Gz acceleration.
  • Blood samples were analyzed for catecholamine levels (noradrenaline, adrenaline).
  • Plasma and supra-optic nucleus (histochemical) were examined for antidiuretic activity.

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Main Results:

  • Increased blood concentrations of noradrenaline and adrenaline were observed, indicating sympatho-adrenergic activation.
  • Elevated antidiuretic response was detected via plasma determinations and histochemical analysis.
  • The antidiuretic response was diminished in a cold environment.

Conclusions:

  • +Gz acceleration induces a significant sympatho-adrenergic reaction in rats.
  • A concurrent increase in antidiuretic activity is associated with G-force exposure.
  • Cold environments may attenuate the antidiuretic response during G-force stress.