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Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
Published on: September 14, 2018
Food allergy: in-vivo diagnostics including challenge
1Division of Pediatric Allergy and Immunology, Arkansas Children's Hospital, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72202, USA. helmrickim@exchange.uams.edu
Current Opinion in Allergy and Clinical Immunology
|April 20, 2002
Summary
Diagnosing food allergies involves confirming symptoms and identifying allergens. The gold standard is the double-blind, placebo-controlled food challenge, crucial for accurate allergy prediction and diagnosis.
Area of Science:
- Immunology
- Allergology
- Clinical Diagnostics
Background:
- Accurate diagnosis of IgE-mediated food allergy requires establishing symptom causality and identifying specific allergens.
- Current diagnostic methods include both in-vitro and in-vivo approaches.
Purpose of the Study:
- To highlight the importance of standardized diagnostic procedures for food allergy.
- To emphasize the role of the double-blind, placebo-controlled food challenge (DBPCFC) as the gold standard.
Main Methods:
- Review of diagnostic procedures for IgE-mediated food allergy.
- Emphasis on the DBPCFC as the gold standard for in-vivo diagnosis.
Main Results:
- DBPCFC is the definitive method for diagnosing specific food allergies.
- Both in-vitro and in-vivo tests provide valuable diagnostic information.
Conclusions:
- Accurate prediction and diagnosis of food allergy depend on standardized methods.
- Diagnostic procedures must be correlated with a standardized DBPCFC for reliable results.
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