Osteoprotegerin and bone loss associated with spaceflight

Microgravity-induced alterations of mouse bones are compartment- and site-specific and vary with age.

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Spaceflight and hind limb unloading induces an arthritic phenotype in knee articular cartilage and menisci of rodents.

Scientific reports·2021

Inhibition of myostatin prevents microgravity-induced loss of skeletal muscle mass and strength.

PloS one·2020

Altered rodent gait characteristics after ~35 days in orbit aboard the International Space Station.

Life sciences in space research·2020

Hemophilia A and B mice, but not VWF-/-mice, display bone defects in congenital development and remodeling after injury.

Scientific reports·2019

A Mouse Model for Skeletal Structure and Function Changes Caused by Radiation Therapy and Estrogen Deficiency.

Calcified tissue international·2019

Analysis of FDA approvals, delays and denials of new drug applications, 2013-2023.

Drug discovery today·2026

Nano alchemy: Ionic liquids transforming metallic particles for medicine.

Drug discovery today·2026

Reassessing galectin inhibition: Lessons for context-selective drug design and translational oncology.

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Pharmacological modulation of ATF6: exploiting a stress-integrative node to overcome drug resistance.

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Protein-ligand interactions by QCM: challenges and resolutions.

Drug discovery today·2026

Validation of AI-enabled surrogate models in quantitative systems pharmacology: a practical, context-of-use-driven review.

Drug discovery today·2026

Regression to the mean can explain saturation of geomagnetic storms.

Nature·2026

Wide-Swath High-Resolution Immersed Grating Spectrometer for Greenhouse Gas Monitoring: Optical Design and Fabrication.

Sensors (Basel, Switzerland)·2026

Chip-integrated metasurface-enabled single-photon skyrmion sources.

Nature communications·2026

Emergent Spacetime Supersymmetry at 2D Fractionalized Quantum Criticality.

Physical review letters·2026

LARES-2 satellite measures frame-dragging effect around the Earth.

Nature·2026

Topological properties of curved spacetime extended Su-Schrieffer-Heeger model.

Journal of physics. Condensed matter : an Institute of Physics journal·2026

Related Experiment Videos

Osteoprotegerin and bone loss associated with spaceflight

Related Concept Videos

Microgravity-induced alterations of mouse bones are compartment- and site-specific and vary with age.

Spaceflight and hind limb unloading induces an arthritic phenotype in knee articular cartilage and menisci of rodents.

Inhibition of myostatin prevents microgravity-induced loss of skeletal muscle mass and strength.

Altered rodent gait characteristics after ~35 days in orbit aboard the International Space Station.

Hemophilia A and B mice, but not VWF-/-mice, display bone defects in congenital development and remodeling after injury.

A Mouse Model for Skeletal Structure and Function Changes Caused by Radiation Therapy and Estrogen Deficiency.

Analysis of FDA approvals, delays and denials of new drug applications, 2013-2023.

Nano alchemy: Ionic liquids transforming metallic particles for medicine.

Reassessing galectin inhibition: Lessons for context-selective drug design and translational oncology.

Pharmacological modulation of ATF6: exploiting a stress-integrative node to overcome drug resistance.

Protein-ligand interactions by QCM: challenges and resolutions.

Validation of AI-enabled surrogate models in quantitative systems pharmacology: a practical, context-of-use-driven review.

Regression to the mean can explain saturation of geomagnetic storms.

Wide-Swath High-Resolution Immersed Grating Spectrometer for Greenhouse Gas Monitoring: Optical Design and Fabrication.

Chip-integrated metasurface-enabled single-photon skyrmion sources.

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Osteoprotegerin and bone loss associated with spaceflight

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