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[TSH pituitary adenoma: case report].

Oswaldo Inácio Tella1, Marco Antonio Herculano, Rosana Delcello

  • 1Disciplina de Neurocirurgia, Universidade Federal de São Paulo, Brasil. detella.ncir@epm.br

Arquivos De Neuro-Psiquiatria
|April 20, 2002
PubMed
Summary

A rare thyroid-stimulating hormone-secreting pituitary adenoma caused hyperthyroidism and vision loss. Surgical resection and radiotherapy were used to treat this complex case.

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Area of Science:

  • Neuroendocrinology
  • Ophthalmology
  • Oncology

Background:

  • Thyroid-stimulating hormone (TSH)-secreting pituitary adenomas are rare tumors causing hyperthyroidism.
  • Pituitary adenomas can cause mass effects, including visual field defects.

Observation:

  • A patient presented with hyperthyroidism and subsequently developed bitemporal hemianopsia.
  • Imaging revealed a pituitary tumor (Hardy-Vezina grade 2, stage C).

Findings:

  • The patient underwent a two-stage surgical approach: initial transsphenoidal biopsy followed by sub-total resection via pterional craniotomy.
  • Histopathological examination confirmed a pituitary adenoma secreting TSH.

Implications:

  • This case highlights the importance of considering TSH-secreting pituitary adenomas in patients with hyperthyroidism and visual disturbances.

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  • Multimodal treatment, including surgery and radiotherapy, may be necessary for effective management.