Schizophrenia, substance use disorders and medical co-morbidity

Barbara Dickey1, Hocine Azeni, Roger Weiss

  • 1McLean Hospital, 115 Mill Street, Belmont, MA 02178, USA.

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Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
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