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Updated: Jan 25, 2026

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
Palliative management of malignant bowel obstruction
Carla Ripamonti1, Eduardo Bruera
1Department of Palliative Care and Rehabilitation, National Cancer Institute, Milan, Italy.
Malignant bowel obstruction (MBO) frequently affects gynecologic cancer patients, especially those with advanced ovarian cancer. MBO is a significant cause of death and complication in these patients.
Area of Science:
- Gynecologic Oncology
- Gastroenterology
- Oncology
Background:
- Malignant bowel obstruction (MBO) is a recognized complication in patients with intra-abdominal and pelvic malignancies.
- It can present as a primary diagnosis or a recurrence following cancer therapy.
- MBO is particularly prevalent in advanced gynecologic cancers.
Purpose of the Study:
- To review the incidence and significance of malignant bowel obstruction in gynecologic oncology.
- To highlight the risk factors associated with MBO in gynecologic cancer patients.
- To emphasize the impact of MBO on mortality in ovarian cancer.
Main Methods:
- Review of retrospective and autopsy studies.
- Analysis of data from gynecological oncology services.
- Examination of patient demographics and tumor characteristics.
Main Results:
- Malignant bowel obstruction (MBO) occurs in 5-51% of gynecologic malignancy patients.
- Ovarian cancer patients experience MBO frequently, often as the primary cause of death.
- Advanced stage (III-IV) and high-grade ovarian tumors increase MBO risk.
Conclusions:
- Malignant bowel obstruction (MBO) is a critical issue in gynecologic oncology, especially for ovarian cancer.
- Early identification of high-risk patients is essential for management.
- MBO significantly impacts survival and quality of life in advanced gynecologic malignancies.
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