Related Experiment Video

Updated: Aug 7, 2026

Rodent Model of Intestinal Ischemia-Reperfusion Injury via Occlusion of the Superior Mesenteric Artery
06:29

Rodent Model of Intestinal Ischemia-Reperfusion Injury via Occlusion of the Superior Mesenteric Artery

Published on: October 20, 2023

Chronic mesenteric ischemia: diagnosis and treatment

D Char1, G Hines

  • 1Division of Vascular Surgery, Stony Brook University Hospital, Stony Brook, New York, USA.

Heart Disease (Hagerstown, Md.)
|April 27, 2002
PubMed

Insights

Chronic mesenteric ischemia, a rare condition from atherosclerosis, often presents subtly. Diagnosis is typically delayed, but angiography and interventions like revascularization offer treatment options.

Area of Science:

  • Vascular Surgery
  • Gastroenterology
  • Diagnostic Imaging

Background:

  • Chronic mesenteric ischemia (CMI) is an infrequent manifestation of systemic atherosclerotic disease.
  • CMI often presents with nonspecific symptoms, leading to diagnostic delays.
  • Delayed diagnosis can result in advanced disease and poorer outcomes.

Purpose of the Study:

  • To highlight the diagnostic challenges and current treatment modalities for chronic mesenteric ischemia.
  • To emphasize the role of selective angiography in diagnosing CMI.
  • To review surgical and endovascular treatment options for symptomatic CMI.

Main Methods:

  • Selective angiography is the established gold standard for diagnosing CMI.
  • Review of literature concerning diagnostic and therapeutic strategies for CMI.
  • Analysis of treatment outcomes for surgical revascularization and catheter-based interventions.

Main Results:

  • Angiography accurately identifies the extent and location of mesenteric artery stenosis or occlusion.
  • Surgical revascularization and endovascular interventions are effective in restoring blood flow.
  • Timely diagnosis and intervention can significantly improve patient outcomes.

Conclusions:

  • Chronic mesenteric ischemia requires a high index of suspicion due to its uncommon and often vague presentation.
  • Selective angiography remains crucial for definitive diagnosis.
  • A spectrum of revascularization techniques, both surgical and endovascular, are available for managing symptomatic CMI.

More Related Videos

Multimodality Diagnosis of Mesenteric Ischemia05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

Visualization of Neutrophil Extracellular Traps in Mesenteric Venules After Mesenteric Ischemia-Reperfusion Injury via Intravital Microscopy07:05

Visualization of Neutrophil Extracellular Traps in Mesenteric Venules After Mesenteric Ischemia-Reperfusion Injury via Intravital Microscopy

Published on: September 27, 2024

Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...