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[Xerosis].

J Mazereeuw1, J-L Bonafé

  • 1Service de Dermatologie, Hôpital Rangueil, 1, avenue Jean-Poulhès, 31403 Toulouse Cedex.

Annales De Dermatologie Et De Venereologie
|April 27, 2002
PubMed
Summary
This summary is machine-generated.

Xerosis, or rough skin, involves changes in the stratum corneum and has many causes. Treatment focuses on local, symptomatic relief with moisturizers and emollients.

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Area of Science:

  • Dermatology
  • Biochemistry

Context:

  • Xerosis presents clinically as rough or coarse skin.
  • Pathophysiologically, it involves structural modifications in the stratum corneum.
  • Abnormalities are observed in keratinization, proliferation, surface lipids, water metabolism, pH, and sebum production.

Purpose:

  • To describe the clinical characteristics, pathophysiology, and etiologies of xerosis.
  • To outline the treatment approaches for xerosis.

Summary:

  • Xerosis manifests in dry skin or ichthyosis-like forms.
  • Etiologies are diverse, including external factors, aging, medications, infections, atopy, deficiencies, systemic diseases, and renal failure.
  • It causes discomfort and affects appearance, necessitating treatment.

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Impact:

  • Highlights the multifaceted nature of xerosis, from its cellular basis to its diverse triggers.
  • Emphasizes the need for symptomatic and localized treatment strategies, including moisturizers and keratolytics like salicylic acid, urea, and alpha-hydroxy acids.