[Prognosis of iron deficiency in women of reproductive age]

Time organization of erythropoiesis and iron metabolism was studied in women of reproductive age. The studies showed that a constant level of erythrocytes and hemoglobin in peripheral blood during the menstrual cycle is maintained due to different intensity of erythropoiesis and iron metabolism. Circadian rhythm of sideremia is characterized by the greatest amplitude of fluctuations during the early lutein phase of the cycle in all healthy women. The difference between serum iron concentrations in the morning and afternoon (8.00-14.00) and in the evening (21.00-24.00) is 4-8 mumol/liter. A lesser difference between the morning and evening concentration of the trace element during the early lutein phase indicates iron dysmetabolism and is prognostically unfavorable with regard to development of iron deficiency.