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Idiopathic external root resorption associated to hypercalciuria.
M C Llena-Puy1, J Amengual-Lorenzo, L Forner-Navarro
1Unidad Docente de Patologia y Terap utica Dental, Departamento de Estomatologia, Universidad de Valencia, Spain. llena@uv.es
Medicina Oral : Organo Oficial De La Sociedad Espanola De Medicina Oral Y De La Academia Iberoamericana De Patologia Y Medicina Bucal
|May 2, 2002
Summary
Idiopathic external root resorption (IERR) in permanent teeth is rare. This study links IERR to mild calciuria and kidney stones in three patients, suggesting a potential connection requiring further investigation.
Area of Science:
- Dentistry
- Nephrology
- Genetics
Background:
- External root resorption (ERR) is common in primary teeth but rare in permanent teeth.
- Idiopathic external root resorption (IERR) lacks a clear cause in most cases.
- Hypercalciuria, often idiopathic, can be linked to nephrolithiasis and genetic factors.
Observation:
- Three cases of IERR in permanent dentition were observed.
- These cases presented with mild calciuria and a history of nephrolithiasis.
- Patients exhibited normal blood calcium levels despite hypercalciuria.
Findings:
- The study highlights the unusual coexistence of IERR, normocalcemic hypercalciuria, and nephrolithiasis.
- This combination suggests a potential underlying systemic link.
- The CLCN5 gene mutation, associated with some hypercalciuria and nephrolithiasis, was not uniformly present.
Implications:
- Further research is needed to explore the association between IERR, hypercalciuria, and nephrolithiasis.
- This finding may prompt a re-evaluation of diagnostic approaches for IERR.
- Understanding this association could lead to novel diagnostic or therapeutic strategies.