[Exocrine function of the pancreas after vagotomy with economical gastric resection]

The authors have studied the effect of vagotomy, associated with an economic gastric resection, on exocrinous function of the pancreas and compared the sequelae of selective and trunkal vagotomy in this respect. The secretin and vagus mechanisms of secretion are analysed. Ten investigations were carried out in patients with duodenal ulcerous disease prior to surgery, and in 68 patients within the terms up to 3 years postoperatively. Vagotomy results in a reliable decrease of the basal amount of pancreatic secretion in maintaining the response to stimulation with hydrochloric acid and insulin hypoglycemia. Changes in exocrinous function of the pancreas were found to be identical after trunkal and selective vagotomy.