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Related Experiment Videos

[Obesity persistent scleredema: study of 49 cases].

V Ray1, A M Boisseau-Garsaud, P Ray

  • 1Service de Dermatologie, CHU de Fort-de-France, Martinique.

Annales De Dermatologie Et De Venereologie
|May 4, 2002
PubMed
Summary

Persistent scleredema is common in patients with obesity, diabetes, and high blood pressure. This rare skin condition is often undiagnosed, highlighting the need for systematic screening in at-risk individuals.

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Area of Science:

  • Dermatology
  • Endocrinology
  • Pulmonology

Context:

  • Scleredema is a rare connective tissue disease.
  • Previous literature suggests scleredema is infrequent.
  • This study investigated scleredema prevalence in at-risk populations.

Purpose:

  • To determine the frequency of persistent scleredema in patients with specific risk factors.
  • To characterize the clinical and histopathological features of scleredema.
  • To identify associated comorbidities and complications.

Summary:

  • A study of 49 patients revealed persistent scleredema in individuals with obesity (95%), diabetes (79.5%), and hypertension (81.5%).
  • Common symptoms included skin infiltration, neck and trunk involvement, limited joint mobility, pruritus, and dyspnea.

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  • A significant association was found with obstructive sleep apnea syndrome (OSAS).

    • Impact:

    • Highlights the high prevalence of scleredema in patients with metabolic and cardiovascular risk factors.
    • Underscores the importance of systematic screening for scleredema in these populations.
    • Reports a novel association between scleredema and obstructive sleep apnea syndrome, warranting further investigation.