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[Anisakis simplex and immediate hypersensitivity reactions].

C Pecquet1, M Danis, F Leynadier

  • 1Centre d'Allergologie, Hôpital Tenon, Paris. catherine.pecquet@tnn.ap-hop-paris.fr

Annales De Dermatologie Et De Venereologie
|May 4, 2002
PubMed
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Anisakis simplex infection can cause severe allergic reactions in humans after consuming raw fish. Early diagnosis and larval removal via endoscopy can alleviate symptoms of gastro-allergic anisakiasis.

Area of Science:

  • Parasitology
  • Immunology
  • Gastroenterology

Background:

  • Anisakis simplex is a nematode parasite of marine mammals.
  • Human infection (anisakiasis) results from ingesting larvae in raw or undercooked seafood.
  • Infections can cause gastrointestinal distress or severe allergic reactions.

Observation:

  • Three cases of acute urticaria with abdominal pain and hypotension after raw fish consumption are presented.
  • Symptoms began 2-6 hours post-ingestion.
  • Diagnosis was confirmed by clinical history and positive Anisakis simplex-specific IgE tests.

Findings:

  • Acute urticaria with abdominal symptoms following raw fish ingestion suggests gastro-allergic anisakiasis.
  • Gastrointestinal endoscopy can visualize and remove Anisakis larvae.

Related Experiment Videos

  • Endoscopic removal aids diagnosis and symptom relief before serological results.

    • Implications:

    • Highlights the potential for severe allergic reactions to Anisakis simplex.
    • Emphasizes the diagnostic and therapeutic role of endoscopy in suspected cases.
    • Informs clinicians about prompt management strategies for foodborne parasitic allergies.