Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

End-to-side neurorrhaphy.

Feng Zhang1, Kenneth A Fischer

  • 1Division of Plastic Surgery, The University of Mississippi Medical Center, Jackson, USA.

Microsurgery
|May 7, 2002
PubMed
Summary
This summary is machine-generated.

End-to-side neurorrhaphy facilitates nerve repair when proximal stumps are unusable. This technique promotes axonal sprouting and reinnervation of the recipient nerve for functional recovery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Implanted electrodes in peripheral nerve stimulation and recording: prospects of their application in electronic prosthesis design.

Journal of long-term effects of medical implants·2009
Same author

[Biocompatibility of silk fibroin nanofibers scaffold with olfactory ensheathing cells].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery·2009
Same author

[Association of tryptophan hydroxylase gene A218C and serotonin transporter gene polymorphism with essential hypertension in Chinese northern Han population].

Zhonghua xin xue guan bing za zhi·2009
Same author

An FES cycling control system based on CPG.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2009
Same author

One example on how colloidal nano- and microparticles could contribute to medicine.

Nanomedicine (London, England)·2009
Same author

[Mutational analysis of Meq, RLORF4, RLORF12 and 132bpr genes of epidemic Marek's disease virus strains highly passaged on chicken embryo fibroblast].

Bing du xue bao = Chinese journal of virology·2009
Same journal

Superficial Palmar Branch of the Radial Artery, Medial Plantar Artery Perforator, and Medial Sural Artery Perforator Free Flaps in Digital Soft Tissue Reconstruction: Comparisons of Clinical Outcomes From a Retrospective Institutional Series.

Microsurgery·2026
Same journal

Lymphovenous Anastomosis for Treatment of Breast Lymphedema Following Delayed Autologous Reconstruction: A Case Report.

Microsurgery·2026
Same journal

Symani-Assisted Microsurgery in Head and Neck Reconstruction: A Systematic Review of Indications, Techniques, and Pooled Analysis of Clinical Outcomes.

Microsurgery·2026
Same journal

Proposing Objective 3D Facial Surface Scanning to Evaluate Surgical Outcomes in Facial Lymphedema.

Microsurgery·2026
Same journal

Closure of Tracheoesophageal Fistula Employing the Superficial Circumflex Iliac Artery Perforator (SCIP) Flap: Report of Three Cases.

Microsurgery·2026
Same journal

Umbilical Inset Incision Type Influences Abdominal Donor Site Healing in Autologous Breast Reconstruction.

Microsurgery·2026
See all related articles

Area of Science:

  • Neurosurgery
  • Regenerative Medicine
  • Peripheral Nerve Injury

Background:

  • End-to-side neurorrhaphy is a surgical technique for nerve repair.
  • It is used when healthy proximal nerve stumps are unavailable for traditional repair.
  • This method aims to restore nerve function by bridging gaps with available donor nerves.

Purpose of the Study:

  • To review the experimental and clinical investigations of end-to-side neurorrhaphy.
  • To analyze key factors influencing the success of this nerve repair strategy.
  • To discuss the potential for functional recovery following end-to-side neurorrhaphy.

Main Methods:

  • Review of animal models and clinical trials concerning end-to-side neurorrhaphy.
  • Analysis of research on axonal collateral sprouting from donor nerves.

Related Experiment Videos

  • Investigation into the effects of surgical interventions like epineurotomy and perineurotomy on nerve regeneration.

    • Main Results:

    • Axonal collateral sprouting is crucial for successful reinnervation in end-to-side neurorrhaphy.
    • The ability of axons to penetrate the recipient nerve's layers, including basal laminae, is essential.
    • Functional plasticity of motoneurons is key for adopting new motor units and behavioral adaptation.

    Conclusions:

    • End-to-side neurorrhaphy presents a viable option for nerve lesions lacking proximal stumps.
    • Optimizing axonal sprouting and penetration into the recipient nerve are critical for clinical success.
    • Further research and clinical trials are necessary to refine this nerve repair technique.