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Updated: Aug 10, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
Neuroendocrine tumors of the thyroid gland
1Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia 19104, USA.
Abstract:
The neuroendocrine lesions of the thyroid are few in number and include C-cell lesions (C-cell hyperplasia and medullary carcinoma), mixed C-cell and follicular-derived tumors, paraganglioma, intrathyroidal parathyroid adenoma, and metastasis to the thyroid from neuroendocrine carcinoma arising elsewhere. However, some follicular-derived lesions of the thyroid can show trabecular and nesting growth patterns characteristic of neuroendocrine tumors. These lesions should also be included in the differential diagnosis of primary and secondary neuroendocrine tumors of the thyroid.
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