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[Metastasis in submandibular gland from a leiomyosarcoma of the uterus]

A J Burgos Sánchez1, M Papi, J Talavera

  • 1Servicio ORL, Hospital General Universitario, Alicante.

Acta Otorrinolaringologica Espanola
|May 10, 2002
PubMed

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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
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The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...