Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dynamic depolarization fields in the cerebral cortex.

Per E Roland1

  • 1Division of Brain Research, Dept of Neuroscience, A3:3, Retzius vaeg 8, Karolinska Institute, S-171 77 Stockholm, Sweden. per.roland@neuro.ki.se

Trends in Neurosciences
|May 10, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

How far neuroscience is from understanding brains.

Frontiers in systems neuroscience·2023
Same author

Local networks from different parts of the human cerebral cortex generate and share the same population dynamic.

Cerebral cortex communications·2022
Same author

Emerging principles of spacetime in brains: Meeting report on spatial neurodynamics.

Neuron·2022
Same author

A three-step reconstruction method for fluorescence molecular tomography based on compressive sensing.

Proceedings of SPIE--the International Society for Optical Engineering·2017
Same author

Space-Time Dynamics of Membrane Currents Evolve to Shape Excitation, Spiking, and Inhibition in the Cortex at Small and Large Scales.

Neuron·2017
Same author

Breaking the Excitation-Inhibition Balance Makes the Cortical Network's Space-Time Dynamics Distinguish Simple Visual Scenes.

Frontiers in systems neuroscience·2017
Same journal

Exercise as a regulator of glymphatic function.

Trends in neurosciences·2026
Same journal

The neural basis of laughter.

Trends in neurosciences·2026
Same journal

Enteric neuroimmune interactions in health and disease.

Trends in neurosciences·2026
Same journal

Atomic insights into the physiological and functional diversity of NMDA receptors.

Trends in neurosciences·2026
Same journal

Cognitive functions of the GPe.

Trends in neurosciences·2026
Same journal

Re-examining the structure-function relationship in tactile corpuscles.

Trends in neurosciences·2026
See all related articles

Large fields in the cerebral cortex depolarize, suggesting dynamic depolarization fields are the brain's core computational units. These fields, engaging numerous neurons, may underlie all cortical functions.

Area of Science:

  • Neuroscience
  • Computational Neuroscience
  • Cognitive Neuroscience

Background:

  • Recent physiological evidence reveals widespread depolarization in the upper layers of the cerebral cortex preceding motor activity.
  • Existing models often focus on columns and hyper-columns as primary computational units.

Purpose of the Study:

  • To propose that dynamic depolarization fields in the cerebral cortex are the fundamental computational elements.
  • To explain how these fields, engaging numerous neurons, could support diverse cortical functions.

Main Methods:

  • Analysis of recent physiological evidence on cortical activity.
  • Theoretical modeling of cooperative neuronal computing in cortical layers I-III.

Main Results:

Related Experiment Videos

  • Identified large-scale depolarization fields in the upper cortical layers as a general phenomenon.
  • Proposed these fields, rather than columns, as the primary computational units.
  • Suggested cooperative neuronal computing in layers I-III explains these fields.

Conclusions:

  • Dynamic depolarization fields represent the core computational elements of the cerebral cortex.
  • These fields are flexible and general, potentially explaining perception, memory, thought, and behavior.
  • Cooperative neuronal computing in superficial cortical layers underlies these widespread dynamic fields.