Signal-to-noise-ratio expressions in optical diffusion tomography

Optical diffusion tomography is a technology that is employed to obtain images of the heterogeneous nature of turbid media by using optical radiation. Noise ultimately limits the achievable spatial resolution in these reconstructed images; therefore it is of interest to develop signal-to-noise-ratio expressions that relate spatial resolution in the images to the underlying system and material properties. In this study, Fourier-domain signal-to-noise-ratio expressions are derived for two types of optical diffusion tomography systems: those that use amplitude-modulated illumination sources and those that use continuous-wave illumination sources. The signal-to-noise-ratio expressions are compared for these two types of systems and are validated by laboratory data.