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Related Experiment Videos

Proteomics and its impact upon biomedical science.

Thomas Marshall1, Katherine M Williams

  • 1Analytical Biochemistry of Group, Institute of Pharmacy, Chemistry & Biomedical Sciences, School of Sciences, The University of Sunderland, UK. tom.marshall@sunderland.ac.uk

British Journal of Biomedical Science
|May 10, 2002
PubMed
Summary

Proteomics studies proteins, offering insights into cellular functions and disease states. This review covers proteomics concepts, technologies, and applications in various medical fields.

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Area of Science:

  • Proteomics
  • Functional Genomics
  • Biochemistry

Background:

  • Proteomics is the study of proteins, analogous to genomics for genes.
  • The proteome, an organism's protein complement, is dynamic and varies with cell type and state.
  • Proteomics reveals cellular perturbations in response to disease and external stimuli.

Purpose of the Study:

  • To review the fundamental concepts and technological advancements in proteomics.
  • To highlight the diverse applications of proteomics in medical and biological sciences.
  • To provide a comprehensive overview for researchers and clinicians.

Main Methods:

  • Integration of state-of-the-art analytical techniques.
  • Application of advanced bioinformatics tools for data analysis.

Related Experiment Videos

  • Comparative analysis of proteomic profiles under different conditions.

    • Main Results:

    • Proteomics provides a functional perspective on gene expression.
    • Dynamic nature of the proteome is crucial for understanding cellular processes.
    • Perturbations in proteomes are indicative of disease states.

    Conclusions:

    • Proteomics is essential for understanding biological systems at a functional level.
    • Technological advancements are expanding the scope and impact of proteomics.
    • Proteomics has broad applications across medical microbiology, pathology, chemistry, immunology, pharmacology, and toxicology.