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Updated: Oct 1, 2026

Expression and Purification of Virus-like Particles for Vaccination
Published on: June 2, 2016
Sequence analysis and expression of a virus-like particle protein, VLP2, from the parasitic wasp Venturia canescens
1Department of Applied and Molecular Ecology, Waite Campus, Adelaide University, Glen Osmond SA 5064, Australia.
Abstract:
Endoparasitoid wasps produce maternal protein secretions, which are transported into the body of insect hosts at oviposition to regulate host physiology for successful development of their offspring. Venturia canescens calyx fluid contains so-called virus-like particles (VLPs) that are essential for immune evasion of the developing parasitoid inside the host. VLPs consist of four major proteins. In this paper, we describe the isolation and molecular cloning of a gene (vlp2) that is a constituent of VLPs and discuss its possible role in VLP structure and function.
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