Related Experiment Video
Updated: Aug 11, 2026

Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography
Published on: April 4, 2012
[Serum leptin level in prepubertal children with simple obesity. Part one]
H Weker1, T Laskowska-Klita, J Ambroszkiewicz
1Zaklad Zywienia, Instytut Matki i Dziecka, Kasprzaka 17a, 01-211 Warszawa, Poland. hweker@imid.med.pl
Abstract:
The aim of the study was to determine the serum leptin level and anthropometric indices (body mass index - BMI) in a group of prepubertal children with simple obesity. These parameters were compared with the values characteristic for the group of slim children. The study showed that serum leptin levels were significantly higher in obese children compared with the group of slim children (p<0.0001). There was a positive correlation (r=0.48; p<0.05) between leptin levels and nutritional status indices expressed by BMI. Results of this study suggest that leptin level in the group of children with simple obesity does not have an effect on satiety, on reduction of appetite or on the increment of adipose tissue. The study showed also that hyperleptinemia might be an effect of leptin resistance.
Related Concept Videos
Regulation of Food Intake
Obesity
Signs of Puberty
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...

