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Carbamazepine-induced acute granulomatous interstitial nephritis
J Hegarty1, M Picton, G Agarwal
1Department of Renal Medicine, Hope Hospital, Salford, UK. jan.hegarty@ticketbox.net
Clinical Nephrology
|May 15, 2002
Abstract:
A 79-year-old man, newly started on carbamazepine, presented with rash, eosinophilia and liver dysfunction progressing to acute renal failure despite discontinuation of the anti-epileptic agent. Percutaneous renal biopsy revealed acute granulomatous interstitial nephritis, which responded successfully to high-dose oral steroid therapy.