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Published on: December 10, 2013
Risk factors associated with severe viral croup in hospitalised Malaysian children
1Department of Paediatrics, University Malaya Medical Centre, Kuala Lumpur, Malaysia. patrick@ummc.edu.my
Insights
Severe viral croup in children is linked to age between 12-24 months and fever. Identifying these risk factors helps guide steroid therapy for hospitalized Malaysian children with viral croup.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- Viral croup is a common respiratory illness in children.
- Identifying risk factors for severe cases is crucial for timely intervention.
Purpose of the Study:
- To determine risk factors for severe viral croup in hospitalized Malaysian children.
- To identify predictors for severe outcomes in pediatric viral croup.
Main Methods:
- Retrospective review of medical records for children under five diagnosed with viral croup (1994-1999).
- Severe viral croup defined by specific clinical signs (stridor, recession, cyanosis, altered consciousness).
- Multivariate logistic regression analysis to identify associated risk factors.
Main Results:
- 14.7% of 122 children experienced severe viral croup.
- Risk factors for severe disease included older age (12-24 months) and presence of fever.
- Older children (16.8 vs 12.6 months) and shorter illness duration (1.7 vs 2.3 days) were noted in severe cases.
- Ventilation was required in only 2.5% of severe cases.
Conclusions:
- Age between 12-24 months and fever are significant risk factors for severe viral croup.
- Early recognition of these factors can guide the selection of children for steroid therapy.
- The overall prognosis for hospitalized viral croup cases remains favorable.
Objective:
To determine the risk factors associated with severe viral croup in hospitalised Malaysian children.
Methodology:
The medical records of children aged less than five years admitted with a diagnosis of viral croup between 1994 and 1999 were reviewed. Severe viral croup was diagnosed in children who had stridor at rest with marked recession associated with central cyanosis or altered level of consciousness. Multivariate logistic regression analysis was performed to identify risk factors associated with severe viral croup.
Results:
Eighteen (14.7%) of 122 children with viral croup were severe. These children were older (mean age 16.8 +/- 7.2 vs 12.6 +/- 6.6 months, p = 0.01) and had a shorter duration of illness prior to admission (1.7 +/- 0.7 days vs 2.3 +/- 1.4 days, p = 0.03). Age between 12 and 24 months (OR 3.8 95% Cl 1.3, 12.7, p = 0.02) and fever (OR 5.7 95% Cl 2.9, 15.6, p = 0.02) were the only risk factors associated with severe viral croup after multivariate logistic regression analysis. Only three children or 2.5 per 100 children admitted with viral croup required ventilation.
Conclusion:
Only a small number of children admitted particularly those between 12 to 24 months with fever developed severe viral croup. Recognition of these risk factors provides a guide in selecting children who will most likely benefit from steroid therapy. The overall outcome was nonetheless favourable.
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