Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ageing: the many-headed monster.

Michael R Rose1, Anthony D Long

  • 1Department of Ecology and Evolutionary Biology, University of California, Irvine, CA 92697-2525, USA. mrrose@uci.edu

Current Biology : CB
|May 15, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<i>Xist</i> expression in male <i>Peromyscus leucopus</i> is associated with restricted chromatin repression and incomplete X-to-autosome dosage compensation.

bioRxiv : the preprint server for biology·2026
Same author

A Matter of Time.

The New England journal of medicine·2026
Same author

Beyond Fixation: Persistent Genetic Variation Under Intense Selection.

bioRxiv : the preprint server for biology·2026
Same author

The illusion of polygenicity in pool-seq genetic mapping studies: insufficient power can mask simple genetic architectures.

Genetics·2026
Same author

Leveraging low-cost short-read sequencing: revolutionizing complex trait genetics.

Molecular biology and evolution·2026
Same author

Things We Do for No Reason™: Routine CD4 testing in hospitalized patients with HIV.

Journal of hospital medicine·2026
Same journal

Hunting ecology predicts eye arrangements in the modular visual system of spiders.

Current biology : CB·2026
Same journal

Sub-second fluctuations between top-down and bottom-up modes distinguish diverse human brain states.

Current biology : CB·2026
Same journal

Queen bees offload pesticide burden to eggs when social buffering is overwhelmed.

Current biology : CB·2026
Same journal

Pitch selectivity in ferret auditory cortex.

Current biology : CB·2026
Same journal

A cell size-dependent competition between geometry and polarity governs nuclear and spindle positioning in early embryos.

Current biology : CB·2026
Same journal

Trophic cascades drive sustainability in the agricultural heritage rice-fish coculture system.

Current biology : CB·2026
See all related articles

Ageing involves uncoordinated pathways, but genome-wide transcription profiling in Drosophila offers a new tool to identify them. This approach helps understand the complex mechanisms of ageing.

Area of Science:

  • Gerontology and Molecular Biology: Focuses on the biological processes of ageing.

Background:

  • Ageing is characterized by a lack of functional coordination among numerous biological pathways.
  • Understanding these pathways is crucial for addressing age-related decline.

Discussion:

  • Genome-wide transcription profiling in Drosophila provides a powerful method to identify key ageing pathways.
  • This technique allows for a comprehensive analysis of gene expression changes during the ageing process.

Key Insights:

  • Transcription profiling reveals uncoordinated pathways contributing to ageing.
  • The study highlights Drosophila as a model organism for ageing research.

Outlook:

  • Future research can leverage this profiling tool to uncover novel therapeutic targets for age-related diseases.

Related Experiment Videos

  • Further investigation into coordinated pathways may lead to interventions promoting healthy ageing.