Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ethanol effects on volitional versus reflexive saccades.

Suzane Vassallo1, Larry A Abel

  • 1School of Orthoptics, La Trobe University, Bundoora, Victoria, Australia. S.Vassallo@latrobe.edu.au

Clinical & Experimental Ophthalmology
|May 16, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Magnetoencephalography during a saccadic eye movement task in anorexia nervosa.

Psychiatry research·2025
Same author

Examining the Visual Search Behaviour of Experts When Screening for the Presence of Diabetic Retinopathy in Fundus Images.

Journal of clinical medicine·2025
Same author

Investigating the cause and maintenance of Anorexia Nervosa - The I-CAN study: Protocol and open call for study sites and collaboration.

Psychiatry research·2023
Same author

A guide to optometrists for appraising and using artificial intelligence in clinical practice.

Clinical & experimental optometry·2023
Same author

Effects of tracker location on the accuracy and precision of the Gazepoint GP3 HD for spectacle wearers.

Behavior research methods·2022
Same author

Video game training in traumatic brain injury patients: an exploratory case report study using eye tracking.

Journal of eye movement research·2022
Same journal

Biopsy of Iris and Anterior Chamber Tumours: Fine Needle, Minimally Invasive and Excision Techniques - Review.

Clinical & experimental ophthalmology·2026
Same journal

Ray-Tracing-Based Intraocular Lens Power Calculation in Combined Cataract Surgery and Descemet Membrane Endothelial Keratoplasty.

Clinical & experimental ophthalmology·2026
Same journal

Comparative Efficacy of Two Defocus Soft Contact Lenses on Axial Length and Choroid in High Myopic Adolescents: Comment.

Clinical & experimental ophthalmology·2026
Same journal

Lessons Learnt From 25 Years of Endophthalmitis: Causes, Microbiology and Visual Outcome Trends.

Clinical & experimental ophthalmology·2026
Same journal

Aqueous Humour Outflow Assessment Using Imaging-Based Techniques in Angle-Based Minimally Invasive Glaucoma Surgery (MIGS): A Systematic Review.

Clinical & experimental ophthalmology·2026
Same journal

Interpreting Hyperreflective Foci in Age-Related Macular Degeneration: A Critical Review of Cell Origins, Evolving Terminology and Clinical Utility.

Clinical & experimental ophthalmology·2026
See all related articles

Moderate alcohol consumption impairs reflexive saccade latency but not accuracy. This suggests alcohol affects brain pathways controlling simple eye movements, not complex inhibitory ones.

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Pharmacology

Background:

  • Eye movements, specifically saccades, are crucial for visual processing and are controlled by complex neural pathways.
  • Alcohol's effects on cognitive and motor functions are well-documented, but its specific impact on different types of saccades requires further investigation.

Purpose of the Study:

  • To investigate the effects of a moderate alcohol dose on reflexive, antisaccade, and self-paced saccades in healthy male subjects.
  • To determine if alcohol consumption impacts saccade latency, accuracy, or error rates.

Main Methods:

  • Seventeen healthy male subjects performed horizontal reflexive saccades, antisaccades, and self-paced saccades.
  • Measurements were taken before and after ingesting a body-weight-related dose of alcohol.

Related Experiment Videos

  • Blood alcohol concentration was monitored, with a mean of 0.044% achieved post-ingestion.

    • Main Results:

    • Reflexive saccade latency significantly increased at a mean blood alcohol concentration of 0.044%, while accuracy remained unimpaired.
    • No significant effects of ethanol were observed on antisaccade latency or accuracy.
    • Antisaccade error rates significantly decreased, suggesting a potential learning effect independent of alcohol's influence.

    Conclusions:

    • Moderate alcohol consumption selectively increases reflexive saccade latency, potentially by modulating connections between the posterior parietal cortex and superior colliculus.
    • Higher-order saccade tasks requiring frontal lobe inhibition appear less affected at this moderate alcohol concentration.
    • Greater alcohol concentrations may impair inhibitory control and higher-order saccade paradigms.