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  3. Aqueous Humour Outflow Assessment Using Imaging-based Techniques In Angle-based Minimally Invasive Glaucoma Surgery (migs): A Systematic Review.
  1. Home
  3. Aqueous Humour Outflow Assessment Using Imaging-based Techniques In Angle-based Minimally Invasive Glaucoma Surgery (migs): A Systematic Review.

Related Experiment Videos

Aqueous Humour Outflow Assessment Using Imaging-Based Techniques in Angle-Based Minimally Invasive Glaucoma Surgery

Bryan Chin Hou Ang1,2,3,4, Eric Jin2, Selvie Yeo2

  • 1Department of Ophthalmology, Tan Tock Seng Hospital, National Healthcare Group Eye Institute, Singapore, Singapore.

Clinical & Experimental Ophthalmology
|June 15, 2026

View abstract on PubMed

Summary
This summary is machine-generated.

Imaging techniques can visualize aqueous humor outflow (AHO) to improve patient selection and surgical outcomes in angle-based minimally invasive glaucoma surgery (MIGS). This review highlights the potential of AHO visualization for enhancing MIGS efficacy.

Keywords:
MIGSaqueous humour outflowglaucomaimaging‐based techniques

Related Experiment Videos

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Glaucoma Surgery

Background:

  • Angle-based minimally invasive glaucoma surgery (MIGS) adoption is increasing, but limitations persist.
  • Imaging techniques offer potential for patient selection and outcome improvement across MIGS stages.
  • This review focuses on imaging for visualizing aqueous humor outflow (AHO) in angle-based MIGS.

Purpose of the Study:

  • To systematically review the application of imaging-based techniques for visualizing aqueous humor outflow (AHO) in angle-based MIGS.
  • To explore how AHO visualization can aid patient selection and surgical prognostication.
  • To assess the potential of imaging to enhance the efficacy of angle-based MIGS.

Main Methods:

  • Systematic literature search of PubMed, EMBASE, and Cochrane Library up to February 16, 2025.
  • Inclusion of cohort, cross-sectional, and observational studies using imaging to visualize AHO in angle-based MIGS.
  • Analysis of 21 studies from an initial 393 identified.

    • Main Results:

    • Various imaging techniques were reported, including HVI, fluorescein/ICG angiography, channelogram, and AS-OCTA.
    • Pre- and intra-operative AHO visualization can predict surgical outcomes and guide MIGS placement.
    • Post-operative AHO assessment allows for comparative analysis of MIGS success and efficacy.

    Conclusions:

    • Imaging techniques visualizing AHO hold significant potential for improving angle-based MIGS outcomes.
    • AHO visualization can enhance patient selection, surgical prognostication, and targeted MIGS placement.
    • Comparative analysis of MIGS efficacy is facilitated by pre-, intra-, and post-operative AHO assessment.