Neutrophils and the pathogenesis of COPD

Two randomised controlled phase 2 studies of the oral neutrophil elastase inhibitor alvelestat in alpha-1 antitrypsin deficiency.

The European respiratory journal·2025

Physiological Small Airways Dysfunction and the Bronchodilator Response in Adults With Asthma and Its Risk Factors: A Retrospective Analysis.

Journal of asthma and allergy·2025

Bacterial colonisation doubles the risk of exacerbation in alpha-1 antitrypsin deficiency.

Respiratory medicine·2025

Proposal and Validation of the Minimum Clinically Important Difference in Emphysema Progression.

Chronic obstructive pulmonary diseases (Miami, Fla.)·2025

Antitrypsin deficiency: still more to learn about the lung after 60 years.

ERJ open research·2024

A novel in vitro cell model of the proteinase/antiproteinase balance observed in alpha-1 antitrypsin deficiency.

Frontiers in pharmacology·2024

Exploring the role of autoimmune conditions in acute interstitial pneumonia.

Chest·2026

Thoracic Ultrasound in Pleural Effusion: A Bedside Practical Approach Introduction.

Chest·2026

Induction Agents for Tracheal Intubation of Critically Ill Patients: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.

Chest·2026

Effect of early versus delayed or no insulin therapy for moderate hyperglycemia in ICU patients: A target trial emulation.

Chest·2026

Integrating Quantitative CT Biomarkers to Enhance COPD Detection in the HANSE Lung Cancer Screening Program.

Chest·2026

Effectiveness of beta-blockers in COPD and CVD: Real-world effects on mortality.

Chest·2026

Immature Neutrophil Phenotype and Enhanced Myeloperoxidase in Male Patients With Chronic Kidney Disease and Cardiovascular Comorbidity.

Acta physiologica (Oxford, England)·2026

PCI for in-stent restenosis of an anomalous right coronary artery.

Annales de cardiologie et d'angeiologie·2026

Prophylactic implantation of implantable cardioverter-defibrillator for the primary prevention of sudden cardiac death after myocardial infarction: protocol for systematic review and meta-analysis of randomised controlled trials.

BMJ open·2026

Direct oral anticoagulants in elderly patients with atrial fibrillation: a decade-long nationwide retrospective cohort study.

BMJ open·2026

Calcium handling in post-infarction arrhythmias - evidence from large animals.

American journal of physiology. Heart and circulatory physiology·2026

Iron Deficiency and Bone Metabolism in Heart Failure.

European journal of heart failure·2026

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Neutrophils and the pathogenesis of COPD

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Two randomised controlled phase 2 studies of the oral neutrophil elastase inhibitor alvelestat in alpha-1 antitrypsin deficiency.

Physiological Small Airways Dysfunction and the Bronchodilator Response in Adults With Asthma and Its Risk Factors: A Retrospective Analysis.

Bacterial colonisation doubles the risk of exacerbation in alpha-1 antitrypsin deficiency.

Proposal and Validation of the Minimum Clinically Important Difference in Emphysema Progression.

Antitrypsin deficiency: still more to learn about the lung after 60 years.

A novel in vitro cell model of the proteinase/antiproteinase balance observed in alpha-1 antitrypsin deficiency.

Exploring the role of autoimmune conditions in acute interstitial pneumonia.

Thoracic Ultrasound in Pleural Effusion: A Bedside Practical Approach Introduction.

Induction Agents for Tracheal Intubation of Critically Ill Patients: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.

Effect of early versus delayed or no insulin therapy for moderate hyperglycemia in ICU patients: A target trial emulation.

Integrating Quantitative CT Biomarkers to Enhance COPD Detection in the HANSE Lung Cancer Screening Program.

Effectiveness of beta-blockers in COPD and CVD: Real-world effects on mortality.

Immature Neutrophil Phenotype and Enhanced Myeloperoxidase in Male Patients With Chronic Kidney Disease and Cardiovascular Comorbidity.

PCI for in-stent restenosis of an anomalous right coronary artery.

Prophylactic implantation of implantable cardioverter-defibrillator for the primary prevention of sudden cardiac death after myocardial infarction: protocol for systematic review and meta-analysis of randomised controlled trials.

Direct oral anticoagulants in elderly patients with atrial fibrillation: a decade-long nationwide retrospective cohort study.

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Neutrophils and the pathogenesis of COPD

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