Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diagnostic lessons from the spectrum study.

R B Lipton1, R K Cady, W F Stewart

  • 1IMR, Stamford, Connecticut, USA.

Neurology
|May 16, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

First results from the LUX dark matter experiment at the Sanford underground research facility.

Physical review letters·2014
Same author

The VANILLA sensor as a beam monitoring device for X-ray radiation therapy.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2013
Same author

Defective CD8+CD28+ regulatory T cell suppressor function in rheumatoid arthritis is restored by tumour necrosis factor inhibitor therapy.

Clinical and experimental immunology·2013
Same author

Long-term mortality following bloodstream infection.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2013
Same author

Preoperative HE4 expression in plasma predicts surgical outcome in primary ovarian cancer patients: results from the OVCAD study.

Gynecologic oncology·2012
Same author

Metformin in obese children and adolescents: the MOCA trial.

The Journal of clinical endocrinology and metabolism·2012
Same journal

Factors Associated With Disability Improvement and Worsening Independent of Attacks in Patients With AQP4-IgG+ NMOSD and MOGAD: A Multicenter Cohort Study.

Neurology·2026
Same journal

Cost-Effectiveness of Intracranial Aneurysm Screening: A Systematic Review.

Neurology·2026
Same journal

Rare Eating Epilepsy: Co-Occurrence of Focal Cortical Dysplasia and Gray Matter Heterotopia.

Neurology·2026
Same journal

Spatiotemporal Associations Between Cortical Microinfarcts and Cortical Superficial Siderosis in Cerebral Amyloid Angiopathy.

Neurology·2026
Same journal

Blood-Brain Barrier Disruption Before Interhospital Transfer for Thrombectomy and Clinical Outcome.

Neurology·2026
Same journal

At Death's Door: Cytosolic Dopamine in Patients With Parkinson Disease.

Neurology·2026
See all related articles

Migraine diagnosis is often missed in patients with disabling headaches. The Spectrum Study found that many patients diagnosed with tension-type headaches actually have migraine, highlighting the need for careful assessment.

Area of Science:

  • Neurology
  • Clinical Trials
  • Headache Disorders

Background:

  • Migraine is a complex neurological condition with variable symptoms.
  • Accurate diagnosis is crucial for effective management.
  • The Spectrum Study aimed to improve understanding of migraine diagnosis.

Purpose of the Study:

  • To evaluate the accuracy of initial migraine diagnoses.
  • To identify lessons learned from the Spectrum Study regarding diagnosis and recruitment.
  • To assess the relationship between headache type, disability, and treatment response.

Main Methods:

  • Compared initial clinical diagnoses with final neurologist diagnoses.
  • Utilized headache diaries for up to 10 attacks per patient.
  • Analyzed diagnostic reclassifications and treatment responses.

Related Experiment Videos

Main Results:

  • 32% of patients initially diagnosed with episodic tension-type headache were reclassified as having migraine.
  • 90% of subjects with high headache disability scores had a migraine-related disorder.
  • Mild headaches in migraineurs can evolve into severe migraine attacks.

Conclusions:

  • Migraine is frequently the correct diagnosis for patients with disabling episodic headaches.
  • High suspicion for migraine is warranted in patients with disabling episodic headaches.
  • Assessing headache-related disability aids in migraine diagnosis.