Distribution of prolactin in selected rat organs and tissues

¹Department of Applied Pharmacy and Drug Technology, Silesian Medical Academy, Sosnowiec, Poland.

International Journal of Tissue Reactions

|May 16, 2002

Abstract:

A single dose of 25 microg prolactin (PRL)/kg of rat body weight was administered to rats subcutaneously. At 1, 2, 3, 4 and 5 h after the injection, selected organs and tissues were taken for analysis. It was found that 1 h after administration, the highest amount of PRL accumulated in the milk (lactiferous) gland, the blood, the ovaries, the pituitary and the liver. Over time, the prolactin content in the selected organs and tissues decreased. PRL is selectively captured by the milk gland, the pituitary, the ovaries, the liver and the heart. Based on the value of the organ or tissue capacity index for PRL, the following order was established for the organs and tissues to which the hormone binds: milk gland > blood > pituitary > ovaries > lungs > liver > cranial bone > spleen > heart > kidneys > muscular tissue > adrenals > adipose tissue > brain.

Related Experiment Videos

Distribution of prolactin in selected rat organs and tissues

Related Concept Videos

Comparison of Vascular Endothelial Growth Factor Concentration in Porcine Kidneys Removed From Living Donors After Cardiac and Brain Death.

Effect of Prolactin on Biochemical and Morphological Parameters of Rabbit Liver in Warm Ischemia.

Analysis of Interactions Between Components of Selected Solution for Organ Perfusion and Preservation.

Concentration of Tumor Necrosis Factor-α and Interleukin-1β in Isolated Porcine Liver Depending on Type of Transgenesis.

Endothelial Nitric Oxide Synthase and Endothelin-1 Expression in the Early Post-Porcine Kidney Autotransplantation Period.

Caspase-3 Expression and ALT, AST, and GGT Activity After 24 Hours of Porcine Liver Cold Storage, Depending on the Type of Transgenesis.

Effects of D-003 (5-200 mg/kg), a mixture of high molecular weight aliphatic acids from sugarcane wax, on bones and bone cell apoptosis in ovariectomized rats.

Effect of D-004, a lipid extract from Cuban royal palm fruit, on histological changes of prostate hyperplasia induced with testosterone in rats.

Pigment epithelium-derived factor is a pericyte mitogen secreted by microvascular endothelial cells: possible participation of angiotensin II-elicited PEDF downregulation in diabetic retinopathy.

Minodronate, a nitrogen-containing bisphosphonate, inhibits advanced glycation end product-induced vascular cell adhesion molecule-1 expression in endothelial cells by suppressing reactive oxygen species generation.

Tissue reaction at the implantation of recombinant human bone morphogenetic protein-2 into the skeletal muscle.

Increasing incidence of melanoma in central Greece: a retrospective epidemiological study.

FvGI-FvCO-FvFT1 pathway activates FvTFL1 in long days to repress flowering in woodland strawberry (Fragaria vesca).

Leaf vessel length and stem-node connectivity in woody angiosperms.

Local Trade-Offs Shape Flower Size Evolution Across Arabidopsis thaliana Distribution.

Phytohormone-microbiome interactions and epigenetic regulation of plant stress responses and priming.

Network analysis of flowering time genes suggests regulatory changes among SOC1 orthologues in response to cold in Brassica napus.

Small peptides play a key role as messengers in plant growth, development and abiotic stress resistance.

Related Experiment Videos

Distribution of prolactin in selected rat organs and tissues

Abstract:

Related Concept Videos

Related Articles