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Updated: Oct 1, 2026
Operant Procedures for Assessing Behavioral Flexibility in Rats
Published on: February 15, 2015
[Effect of disruption of the entopeduncular nucleus on rat behavior in simultaneous discrimination and open field
G T Sarkisov1, L M Karapetian, Zh S Sarkisian
1Institute of Zoology, National Academy of Sciences of Armenia, Yerevan, Armenia.
Abstract:
The influence of unilateral destruction of n. entopeduncularis on learning and retention of simultaneous discrimination in a T-maze and adaptation in the open filed was studied in 29 adult rats. Destruction of n. entopeduncularis in rats resulted in appreciable deviations from the normal behavior during realization of earlier acquired simultaneous discrimination and slowing down of the acquisition of a new habit. Differences in behavioral activity of the lesioned animals in the maze and open field were revealed.
