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Related Experiment Videos

Sevoflurane induction in the elderly.

K F Cheong1, T S Teh

  • 1Department of Anaesthesia, National University Hospital, Singapore.

The Medical Journal of Malaysia
|May 17, 2002
PubMed
Summary
This summary is machine-generated.

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Sevoflurane induction at 2% or 4% is a suitable alternative for elderly patients, offering minimal cardiovascular effects. Intravenous Thiopentone induction was significantly faster but caused a greater drop in blood pressure.

Area of Science:

  • Anesthesiology
  • Geriatric Medicine

Background:

  • Induction of anesthesia in the elderly requires careful consideration of cardiovascular stability.
  • Sevoflurane is an inhaled anesthetic agent with potential benefits for induction.

Purpose of the Study:

  • To compare the efficacy and safety of sevoflurane (2% and 4%) versus intravenous Thiopentone for anesthetic induction in elderly patients.

Main Methods:

  • A comparative study involving 60 unpremedicated elderly patients.
  • Induction of anesthesia using 2% sevoflurane, 4% sevoflurane, or intravenous Thiopentone.
  • Monitoring of induction time, cough reflex, and mean arterial pressure changes.

Main Results:

  • Intravenous Thiopentone induction was significantly faster (27±5 seconds) than 2% (109±36 seconds) or 4% sevoflurane (71±24 seconds).

Related Experiment Videos

  • The greatest reduction in mean arterial pressure occurred with Thiopentone, followed by 4% and 2% sevoflurane.
  • Coughing was infrequent, occurring in one patient for Thiopentone and 2% sevoflurane, and two patients for 4% sevoflurane.

    • Conclusions:

    • Both 2% and 4% sevoflurane provide suitable conditions for anesthetic induction in the elderly.
    • Sevoflurane induction is associated with minimal cardiovascular disturbances compared to Thiopentone.